This week’s topics include occluding the atrial appendage and stroke, a pragmatic
smoking trial, a relative rise in lung cancer among women, and the benefits of egg
0:37 Disturbing rise in lung cancer among women 1:37 Over the decades has decreased more in men 2:35 A pragmatic trial of smoking cessation interventions 3:28 Only 20% even wanted to try 4:28 Still remains the greatest preventable cause of death 5:10 Surgical occlusion of left atrial appendage 6:10 Seems to be clear to do it 7:10 They were more likely to develop ongoing a-fib 7:46 Egg consumption and cardiovascular outcomes 8:49 One egg per day had lower risk 9:35 Americans have more ischemic heart disease 10:35 End
This week’s topics include the Ebola vaccine, stroke risk and resolved a-fib, an antibody
for migraine prevention, and cannabis and tobacco smoking by parents.
0:36 Ebola vaccine 1:36 Persistent neutralizing antibodies 2:36 May not return for boosters 3:36 These are worldwide concerns 4:10 Cannabis and tobacco use in parents 5:10 More prevalent in men 6:06 Resolved a-fib and stroke 7:08 Give blood thinners and decrease risk 8:09 Migraine prevention 9:09 Decreased by 1.5 headaches per month 10:08 Clinical entity is tip of the iceberg 10:45 End
This week’s topics include crowdfunding for stem cell therapies, USPSTF recommendations
for prostate cancer screening, MRI guided biopsy of the prostate, and testing blood
for Zika virus.
0:31 Zika virus screening of blood donations 1:31 Cost of about $1 million to prevent one case 2:31 Traveled into the US and gave blood 3:15 PSA screening recommendations 4:15 Screening 1000 men 5:14 Appropriate strategy to follow 5:26 Utility of MRI for targeted biopsy of prostate 6:27 Have a sonogram 7:15 Crowdfunding for stem cell therapy 8:15 How many soliciting? 9:15 FDA now looking 10:20 End
This week’s topics include the best blood vessel for cardiac bypass grafts, rates
of autism, five healthy lifestyle factors and their impact on mortality, and managing
0:37 Autism rates nationally 1:38 Are there differences in sites? 2:36 Overall increased from 13 per 1000 to 29 per 1000 3:15 Five lifestyle factors and lifespan 4:15 For men and women longer life 5:15 Smoking makes the most difference 6:01 Managing COPD 7:01 Randomized to triple or dual therapy 8:01 Radial artery versus the saphenous vein for CABG 9:01 Internal mammary on the LAD 10:37 End
This week’s topics include best treatment of venous leg ulcers, cannabis and cognition,
anticlotting agents after bypass grafting, and caffeine and childhood obesity.
0:38 Cannabis and cognition in young people 1:38 Didn’t see an impact after 72 hours 2:38 Neurodevelopment ongoing in this age group 3:35 Aspirin and ticagrelor after bypass 4:32 End of a year 89% were open 5:31 Keep people on two agents? 5:49 Caffeine consumption during pregnancy and childhood obesity 6:47 Excess childhood weight persisted to eight years 7:45 Tell mothers to use the lowest caffeine 7:57 Leg ulcer treatment 8:57 Ablation in first two weeks 9:50 Different types of ablation 10:28 End
This week’s topics include preventing falls in the elderly, ambulatory versus clinic
blood pressures, benefits of statin use, and how much alcohol is okay to consume.
0:36 How much alcohol consumption is safe 1:36 Standard drink amount 2:36 Variations worldwide 3:33 Different types of death, linear increase 4:00 Who benefits from statins? 5:04 Newer trials with lower LDL at baseline 6:03 Ambulatory blood pressure versus clinical measurement 7:03 Different categories of high blood pressure 8:03 Masked hypertension had three times mortality 8:44 Falls in the elderly 9:44 Exercise most beneficial 10:38 End
This week’s topics include safety of smoking cessation medicines, a nationwide look
at health, predictors of COPD in childhood, and neuron growth and health in one part
of the brain.
0:41 A state by state look at health 1:41 Huge geographic difference in life expectancy 2:41 Have control over many factors 3:40 Can intervene with policy 4:01 New neurons in the hippocampus 5:02 Fairly small autopsy study 5:35 Safety of smoking cessation medicines 6:35 Extended study for full year 7:35 Effective in at least a third of individuals 7:52 Antecedents of COPD in childhood 8:50 Factors can be modified 9:52 Parental history of asthma 10:52 End
This week’s topics include diagnosing cellulitis, managing pleural effusion, antibiotics
and antacids in children and allergy, and loss of wealth and mortality.
0:38 Managing pleural effusion in people with cancer 1:39 Worked well on outpatient basis 2:33 Could be done in US? 3:08 Antibiotics and acid suppression in infants and allergy 4:08 Twice as likely to develop allergic reactions 5:08 Biologically plausible 5:44 Health and wealth 6:43 Increased mortality to same level as poverty 7:33 Cellulitis diagnosis 8:33 Don’t recommend routine imaging 9:32 Avoid these tests 10:18 End
This week’s topics include sinusitis treatment, low back pain management, waning mumps
immunity, and e-cigarettes and quitting attempts.
0:37 Mumps immunity waning 1:32 A booster should be assessed 2:33 Sequelae of mumps in adults 3:10 Use of e-cigarettes to assist in quitting smoking 4:12 Those using e-cigs were 50% or more less likely to quit 5:12 Damning evidence on e-cigs 5:46 Low back pain management 6:46 Call out to global health community 7:45 First line of therapy is nonpharmacologic 8:28 Sinusitis and antibiotic use 9:28 How should a patient approach this? 10:24 End
This week’s topics include treating infants with bronchiolitis, orthotics for heel
pain, medications for behavioral issues in people with dementia, and treating Helicobacter
pylori infection in people with early gastric cancer.
0:40 Orthotics for plantar heel pain 1:40 Not really helpful 2:41 Risk factors include low arch 3:01 CMS and use of medicines in people with dementia 4:01 Increased use of mood-altering drugs 5:01 Increases risk of death 5:45 Infection with H.pylori and gastric cancers 6:45 Chronic inflammation and cell change 7:45 Don’t know if screening helps in low and intermediate risk 8:23 High flow oxygen in infant bronchiolitis 9:23 Stabilized condition 10:51 End
This week’s topics include mortality statistics since 1980 across the US, domestic
healthcare costs, an iPad intervention for colorectal cancer screening, and real world
experience with clot retrieval in stroke.
0:40 An iPad intervention for colorectal ca screening 1:40 I need colorectal cancer screening 2:42 Hopefully hooked into having screening 3:02 Real world experience with clot retrieval after stroke 4:03 Lower complication rate 5:05 Patterns of mortality relative to substance abuse and self harm 6:08 This data helpful, county by county 7:03 Rural area more problematic 7:15 Medical costs in the US 8:15 Why costs so high? 9:15 Just prolong a few months 10:11 End
This week’s topics include the dangers of e-cigarettes, steroids and asthma, five
types of diabetes, and a single PSA measurement and outcomes.
0:41 Looking at metabolites of e-cigarettes 1:41 Increased organic compounds in blood 2:43 Targeting to this population 3:00 One time screening for prostate cancer 4:00 Did not decrease prostate cancer mortality at all 5:00 New tests will become available 5:17 Five subtypes of diabetes 6:17 Severe insulin deficient 7:16 Previously only classified by HbA1c 8:19 Metabolic measures 8:39 300 million people worldwide with asthma 9:45 Make sure they are optimally managed 10:33 End
This week’s topics include fluids best for resuscitation, a blood test for 8 cancers,
managing chronic pain for disadvantaged folks, and varicose veins and other circulatory
0:43 CancerSEEK, a blood test for cancer 1:44 For some of the cancers no screening test exists 2:44 Compared to a normal population 3:45 Specificity in a healthy population may not apply 4:33 Managing chronic pain in a disadvantaged population 5:33 Tough population with tailored CBT 6:33 Varicose veins and DVT 7:33 An association perhaps with common risk factors 8:22 Critically ill patients and fluid use 9:23 Helps kidneys but no difference in mortality 10:48 End
This week’s topics include anticoagulation after knee or hip surgery, proper treatment
of ARDS, dermatology consults for cellulitis in the hospital, and avoiding delirium
in the ICU.
0:39 Management of ARDS 1:37 Mechanical ventilation is important 2:34 Volume of air with each breath 3:21 Anticoagulation after hip or knee replacement 4:22 Aspirin versus NOAC 5:23 No studies of only aspirin 5:35 Benefits of in hospital dermatologists 6:35 Got correct diagnosis in cellulitis 7:31 Prevention of delirium in the ICU 8:31 Treatment with haloperidol did not improve outcomes 10:14 End